IGF-1
OtherA potent growth hormone that regulates cell growth. Higher levels associated with increased cancer risk. Centenarians have lower levels. Dampening IGF-1 signaling shifts body from growth to maintenance/repair mode.
Biological Mechanisms
How IGF-1 works at a cellular level.
- PromotesFuels Cancer Cell Proliferation
When PI3K is activated by insulin and IGF-1, the insulin-like growth factor, the cell is able to devour glucose at a great rate
Sources
- How Not to Age
- Outlive