Caffeine
PhytochemicalExtends yeast lifespan by targeting TORC1
Food Sources
Foods that contain Caffeine.
- Coffee
Source: How Not to Age
Health Benefits
Health conditions that Caffeine may influence, based on research.
Improves
- Androgenetic Alopecia
Dhurat 2017: topical caffeine liquid studied for male androgenetic alopecia; Fischer 2014: caffeine affected hair shaft elongation in vitro
Source: How Not to Age
Protects Against
- Parkinson's disease
Compounds which may play a role include caffeine.
Source: Nutrition, Food and Diet in Ageing and Longevity
Biological Mechanisms
How Caffeine works at a cellular level.
- PromotesmTOR Suppression
Caffeine extends yeast lifespan by targeting TORC1; coffee consumption decreases hepatic mTOR levels
- PromotesActivates heat shock proteins that repair damaged proteins
Coffee extract and caffeine enhance the heat shock response and promote proteostasis in an HSF-1-dependent manner.
- PromotesDisrupts Sleep Quality
The half-life of caffeine is up to six hours. It works by inhibiting the receptor for adenosine, which normally helps us go to sleep. A slow metabolizer should stop at one or two cups before noon; Caffeine is discussed as a factor affecting sleep quality in the sleep chapter index
- PromotesAutophagy
Caffeine found to be a potent autophagy stimulant
Recipes with Caffeine
Recipes featuring foods that contain Caffeine.
Sources
- How Not to Age
- Nutrition, Food and Diet in Ageing and Longevity
- Outlive