Hydroxytyrosol
Food Sources
Foods that contain Hydroxytyrosol.
- Extra-Virgin Olive Oil
Virgin olive oils contain phenolic compounds such as oleuropein, hydroxytyrosol, and oleocanthal; Hydroxytyrosol (50-70%) represents the main constituent of the olive pulp extract; Extra virgin olive oil contains hydroxytyrosol; Hydrolysis derivatives include hydroxytyrosol and tyrosol found in olive oil secoiridoids
Source: Nutrition, Food and Diet in Ageing and Longevity
Health Benefits
Health conditions that Hydroxytyrosol may influence, based on research.
Protects Against
- Alzheimer's disease50 mg/kg diet
HT supplementation at 50 mg/kg diet improved cognitive functions and reduced Abeta42 and pE3-Abeta plaque in cortex of TgCRND8 mice
Source: Nutrition, Food and Diet in Ageing and Longevity
- Rheumatoid arthritis4 capsules/day freeze-dried olive vegetation water
Olive polyphenol extract administered as 4 capsules/day to 90 arthritis patients induced potent anti-inflammatory activity with reduction in pain, swelling, and inflammation biomarkers CRP and homocysteine
Source: Nutrition, Food and Diet in Ageing and Longevity
Biological Mechanisms
How Hydroxytyrosol works at a cellular level.
- PromotesBlocks Inflammatory Enzymes
Olive oil polyphenol hydroxytyrosol reduces PGE2 due to inhibition of COX-2 activity in human monocytes; also inhibits NF-kB and TNF-alpha
- PromotesReduces inflammation
Hydroxytyrosol is the major anti-inflammatory compound in aqueous olive extracts; at low doses exerts anti-inflammatory, antioxidant, anti-aging and anti-proliferative effects; Direct anti-inflammatory effect exerted by hydroxytyrosol (olive butter/oil); targets NF-kB pathway
- PromotesBoosts BDNF Levels
HT at 45 mg/kg BW/day induces increase of BDNF in mice, favors recovery after ischemic stroke by improving learning and motor impairments
- PromotesBoosts glutathione antioxidant levels
A single dose of 2.5 mg HT administered orally significantly increased total glutathione antioxidant levels in plasma of healthy volunteers
- PromotesLowers LDL Cholesterol
Doses as low as 5 mg HT/day produced a remarkable reduction of high MW cholesterol while HDL was unchanged or improved in patients with high cholesterol
Recipes with Hydroxytyrosol
Recipes featuring foods that contain Hydroxytyrosol.
Sources
- Nutrition, Food and Diet in Ageing and Longevity