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Lycopene

Phytochemical

The red pigment in tomatoes. No overall effect of supplementation on IGF-1 levels found in six studies.

Food Sources

Foods that contain Lycopene.

  • Tomatoes

    Source: How Not to Age

  • Tomato Paste

    Source: How Not to Age

  • Tomato

    Source: How Not to Age

  • Tomato Juice (Salt-Free)

    Tomato juice appears to be the one common juice that may actually be healthier than the whole fruit. Processing boosts availability of lycopene by as much as fivefold.

    Source: How Not to Die

  • Watermelon

    Lycopene found in red tomatoes, watermelon, grapefruit, guava

    Source: Nutrition, Food and Diet in Ageing and Longevity

Health Benefits

Health conditions that Lycopene may influence, based on research.

Improves

  • Gingivitis1 tomato/day equivalent

    Double-blind RCT: amount of lycopene in 1 tomato/day (about 1 tablespoon tomato paste) significantly reduced gingivitis within 1 week; also improved gum bleeding in periodontitis | Lycopene improved gingivitis in an RCT and showed benefits as adjunctive treatment for chronic periodontitis

    Source: How Not to Age

Reduces Risk Of

  • All-Cause Mortality

    Tomato and lycopene consumption inversely associated with total and cause-specific mortality in population-based cohort study

    Source: How Not to Age

  • Prostate cancer

    Lycopene from tomatoes, watermelon, strawberry, pink guava supports prostate health

    Source: Nutrition, Food and Diet in Ageing and Longevity

  • Cancer

    Source: Young Forever

Protects Against

  • Osteoporosis

    Lycopene supplementation decreases bone resorption marker in postmenopausal women

    Source: How Not to Age

  • Skin Aging

    Cutaneous lycopene concentration correlated with skin roughness

    Source: How Not to Age

  • Depression

    Among the carotenoids, lycopene (the red pigment in tomatoes) has the highest antioxidant activity and is associated with reduced depression odds.

    Source: How Not to Die

  • Cardiovascular Disease

    Lycopene has protective effect on cardiovascular system, positive effect on neurodegenerative diseases including Alzheimer's and Parkinson's

    Source: Nutrition, Food and Diet in Ageing and Longevity

  • Neurodegenerative Disease

    Lycopene has protective effect on cardiovascular system, positive effect on neurodegenerative diseases including Alzheimer's and Parkinson's

    Source: Nutrition, Food and Diet in Ageing and Longevity

  • Parkinson's disease

    Lycopene relieves oxidative stress, increases NADH dehydrogenase and SOD activity in the corpus striatum and lowers malondialdehyde levels

    Source: Nutrition, Food and Diet in Ageing and Longevity

  • Alzheimer's disease

    Lycopene can stop activities of secretases responsible for processing of amyloid precursor protein, leading to neuroprotection in Alzheimer's disease

    Source: Nutrition, Food and Diet in Ageing and Longevity

  • Heart disease

    lycopene, a carotenoid antioxidant that's known to help control cholesterol and protect against free radicals

    Source: The Young Forever Cookbook

Biological Mechanisms

How Lycopene works at a cellular level.

  • PromotesLowers IGF-1

    Tomato lycopene extract supplementation decreases IGF-1 levels in colon cancer patients

  • PromotesHormesis

    Terpenoids including lycopene, lutein, and beta-carotene are hormetin molecules found in various foods (kale, spinach, asparagus, broccoli, pepper, lettuce, apricot) reported for effects on ageing and lifespan.

  • PromotesSuppresses NF-kB signaling that drives cancer growth

    Lycopene suppresses LPS-induced NO and IL-6 production by suppressing ERK, p38MAPK, NF-kB, and HMGB1 activation

  • SupportsSupports Brain Health and Function

    lycopene, a phytonutrient that helps support cognitive and heart health

  • PromotesLowers cholesterol

    lycopene, a carotenoid antioxidant that's known to help control cholesterol

  • PromotesPrevents cancer cell growth

    When cooked, tomatoes release higher amounts of lycopene, a cancer-fighting antioxidant

Recipes with Lycopene

Recipes featuring foods that contain Lycopene.

Sources

  • How Not to Age
  • How Not to Die
  • Nutrition, Food and Diet in Ageing and Longevity
  • The Young Forever Cookbook
  • Young Forever