Neurodegenerative Disease

Foods That May Help

Foods linked to Neurodegenerative Disease in the research literature.

• EchinaceaProtects against

  Echinacoside, a natural phenylethanoid glycoside from Echinacea, shows neuroprotective effects by downregulating intracellular ROS, p38MAPK, caspase and upregulating pERK MAPK and SIRT1

  Source: Nutrition, Food and Diet in Ageing and Longevity

• Bitter Gourd (Bitter Melon)Reduces risk of

  Bitter gourd plays an important role in the prevention of neurodegenerative diseases

  Source: Nutrition, Food and Diet in Ageing and Longevity

Compounds That May Help

Bioactive compounds linked to Neurodegenerative Disease in the research.

• B vitaminsProtects against

  B1 deficiency is included in the pathogenesis of ageing-related diseases such as dementia, Alzheimer's disease, Parkinson's disease, and Huntington's disease

  Source: Nutrition, Food and Diet in Ageing and Longevity

• FolateProtects against

  Increased homocysteine cytotoxicity has been conferred to have a role in neuronal plasticity, and neurodegenerative diseases such as Alzheimer's, Parkinson's, and Huntington's disease.; Folate prevents neurodegenerative disorder; supports immune health. Found in beans, legumes, citrus fruits, green leafy vegetables

  Source: Nutrition, Food and Diet in Ageing and Longevity

• LycopeneProtects against

  Lycopene has protective effect on cardiovascular system, positive effect on neurodegenerative diseases including Alzheimer's and Parkinson's

  Source: Nutrition, Food and Diet in Ageing and Longevity

• CurcuminReduces risk of

  Curcumin reduces the incidence of neuroinflammation; lowers the levels of C-reactive protein; functions as antioxidant, chemopreventive, chemosensitizer, chondroprotective and anti-inflammatory agent

  Source: Nutrition, Food and Diet in Ageing and Longevity

• LuteolinReduces risk of

  Luteolin inhibits IL-1beta and TNF-alpha by regulating STAT3, NF-kB, and AP-1; may reduce risk of inflammatory diseases such as neurodegenerative diseases and cancer

  Source: Nutrition, Food and Diet in Ageing and Longevity

• EGCGReduces risk of

  Green tea catechin EGCG mimics the anti-aging properties of metformin and rapamycin; has a neuroprotective role; reduces UVR-induced DNA damage and lowers ROS

  Source: Nutrition, Food and Diet in Ageing and Longevity

• BerberineProtects against
  1 micromolar

  Low dose berberine (1 microM) exhibits hormetic and neuroprotective effects by up-regulating PI3K/AKT/Bcl-2 cell survival and Nrf2/HO-1 antioxidative signaling pathways in models of neurodegeneration

  Source: Nutrition, Food and Diet in Ageing and Longevity

• SpermidineProtects against

  Supplementation with autophagy-activating spermidine has been shown to protect against neurodegeneration and cognitive decline in animal models

  Source: Nutrition, Food and Diet in Ageing and Longevity

Risk Factors

Foods and compounds that may contribute to Neurodegenerative Disease.

• Iron

  During ageing, iron accumulates in different brain regions creating an imbalance between ROS production and antioxidant defence. Iron accumulation in the brain increases susceptibility to neurodegenerative diseases.

  Source: Nutrition, Food and Diet in Ageing and Longevity

Sources

• Nutrition, Food and Diet in Ageing and Longevity