Berberine
PhytochemicalA compound found in barberries that activates AMPK by mildly impairing mitochondrial function, used widely in China for diabetes management.
Food Sources
Foods that contain Berberine.
- Barberries
Source: How Not to Age
Health Benefits
Health conditions that Berberine may influence, based on research.
Protects Against
- Aging
Prolonged lifespan and stimulated locomotor activity in Drosophila
Source: How Not to Age
- Neurodegenerative Disease1 micromolar
Low dose berberine (1 microM) exhibits hormetic and neuroprotective effects by up-regulating PI3K/AKT/Bcl-2 cell survival and Nrf2/HO-1 antioxidative signaling pathways in models of neurodegeneration
Source: Nutrition, Food and Diet in Ageing and Longevity
Reduces Risk Of
- Insulin resistance
Berberine appears to act through the toll-like receptor LPS-TLR4 signaling pathway to reduce insulin resistance in mice on a high-fat diet
Source: How We Age
Improves
- Type 2 diabetes
Source: Young Forever
Biological Mechanisms
How Berberine works at a cellular level.
- PromotesAMPK activation
Berberine activates AMPK by mildly impairing mitochondrial function.
- PromotesAutophagy
- PromotesImpairs mitochondrial function
Recipes with Berberine
Recipes featuring foods that contain Berberine.
Sources
- How Not to Age
- How We Age
- Nutrition, Food and Diet in Ageing and Longevity
- Young Forever