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Turmeric

The single most anti-inflammatory food per the Dietary Inflammatory Index.

Okinawan diet

Also known as: turmeric powder

Active Compounds

Bioactive compounds found in Turmeric, based on research from longevity science.

Health Benefits

Health conditions and aging processes that Turmeric may influence, based on the source research.

Protects Against

  • DNA DamageA tenth of a teaspoon of cooked turmeric for one week; an eighth of a teaspoon daily cut DNA damage by 55%

    Led the pack in DNA protection among spices tested

    Source: How Not to Age

  • Colorectal cancer

    Curcumin reduced aberrant crypt foci by nearly 40 percent in 30 days. Six months of curcumin plus quercetin decreased polyp number and size by more than half.

    Source: How Not to Die

  • Pancreatic Cancer

    Curcumin stalled advanced pancreatic cancer in one-third of patients (5 of 15) at MD Anderson Cancer Center, with zero adverse effects.

    Source: How Not to Die

Improves

  • Knee Osteoarthritisabout 1/2 teaspoon daily

    16 RCTs: significantly reduced pain and improved function vs placebo, similar to NSAIDs with better safety

    Source: How Not to Age

  • Alzheimer's diseaseabout 1/4 teaspoon daily

    Remarkable case series of 3 Alzheimer's patients dramatically improving on about 1/4 teaspoon/day; but curcumin supplements failed in 2 RCTs; whole turmeric may be greater than sum of parts

    Source: How Not to Age

  • Ulcerative Colitis

    More than 50 percent of ulcerative colitis patients achieved remission within just one month on curcumin compared to none on placebo; Curcumin in combination with mesalamine induces remission in mild-to-moderate ulcerative colitis (Lang et al. 2015)

    Source: How Not to Die

  • Endothelial dysfunction

    Daily ingestion of curcumin can improve endothelial function just as well as up to an hour a day of aerobic exercise

    Source: How Not to Die

  • Osteoarthritis

    Curcuma domestica extracts were comparable to ibuprofen for knee osteoarthritis (Kuptniratsaikul et al. 2014)

    Source: How Not to Die

  • Lupus Nephritis

    Oral turmeric supplementation decreases proteinuria, hematuria, and systolic blood pressure in lupus nephritis patients (Khajehdehi et al. 2012)

    Source: How Not to Die

Reduces Risk Of

  • Chronic inflammation (inflammaging)1/4 teaspoon/day

    Curcumin has been shown to effectively treat rheumatoid arthritis better than the leading drug and is also effective for osteoarthritis, lupus, and inflammatory bowel disease

    Source: How Not to Die

  • Rheumatoid arthritis

    Curcumin showed efficacy and safety in patients with active rheumatoid arthritis (Chandran & Goel 2012)

    Source: How Not to Die

  • Cancerquarter teaspoon daily

    Curcumin-free turmeric exhibits anti-inflammatory and anticancer activities (Aggarwal et al. 2013); whole turmeric may be better than curcumin alone

    Source: How Not to Die

Biological Mechanisms

How Turmeric works at a cellular level.

  • PromotesReduces inflammation

    The single most anti-inflammatory food per the Dietary Inflammatory Index. | Randomized controlled trials clearly show a drop in inflammatory markers | Less than 1/10 teaspoon per day suppresses release of inflammatory mediators like TNF | Curcumin has anti-inflammatory and neuroprotective effects; bioavailability confirmed from herbs and spices in humans

  • PromotesBoosts Antioxidant Enzymes

    Catalase enzyme activity boosted by more than 50 percent

  • PromotesAntioxidant Defense

    50:1 ratio of turmeric to black pepper reduced oxidative damage by 50 percent before radiation therapy

  • PromotesBoosts BDNF Levels
  • InhibitsStomach Fat Oxidation

    Half teaspoon to half pound of ground beef cuts MDA by ~20%; adding black pepper doubles the effect

  • PromotesReduces lipid peroxidation

    Turmeric and black pepper decreased lipid peroxidation in meat patties during cooking

  • PromotesSuppresses NF-kB signaling that drives cancer growth

    Turmeric inhibits inflammatory nuclear factor NF-kB and NF-kB-regulated gene products (Kim et al. 2012)

  • PromotesStimulates gallbladder contraction and bile flow

    Curcumin stimulates gallbladder contraction; people with gallstones should be cautious (Rasyid & Lelo 1999)

  • PromotesActivates Nrf2

    Food extracts such as coffee, turmeric, rosemary, broccoli, thyme, clove and oregano strongly induce Nrf2-mediated SR.

Dosage Recommendations

Specific amounts mentioned in the research literature.

  • A tenth of a teaspoon of cooked turmeric for one week; an eighth of a teaspoon daily cut DNA damage by 55%for DNA Damage

    Led the pack in DNA protection among spices tested

    Source: How Not to Age

  • 3/4 teaspoon per day for a monthfor DNA Damage

    Turmeric reduced DNA damage by about 40 percent in a study of people eating spices

    Source: How Not to Age

  • 3/4 teaspoon per day for a monthfor Boosts Antioxidant Enzymes

    Catalase enzyme activity boosted by more than 50 percent

    Source: How Not to Age

  • Half teaspoon of 50:1 turmeric-to-black-pepper mix for 5 daysfor Antioxidant Defense

    50:1 ratio of turmeric to black pepper reduced oxidative damage by 50 percent before radiation therapy

    Source: How Not to Age

  • about 1/2 teaspoon dailyfor Knee Osteoarthritis

    16 RCTs: significantly reduced pain and improved function vs placebo, similar to NSAIDs with better safety

    Source: How Not to Age

  • about 1/4 teaspoon dailyfor Alzheimer's disease

    Remarkable case series of 3 Alzheimer's patients dramatically improving on about 1/4 teaspoon/day; but curcumin supplements failed in 2 RCTs; whole turmeric may be greater than sum of parts

    Source: How Not to Age

  • less than 1 teaspoon dailyfor DNA Damage

    Smokers eating less than a teaspoon of turmeric daily reduced DNA-mutation rate by up to 38 percent.; A single pinch of turmeric once a day for a week cut the number of cells with DNA damage in half; Less than a teaspoon of turmeric daily reduced the DNA-mutation rate of smokers' urine by up to 38%.

    Source: How Not to Die

  • 1/4 teaspoon/dayfor Chronic inflammation (inflammaging)

    Curcumin has been shown to effectively treat rheumatoid arthritis better than the leading drug and is also effective for osteoarthritis, lupus, and inflammatory bowel disease

    Source: How Not to Die

  • quarter teaspoon dailyfor Cancer

    Curcumin-free turmeric exhibits anti-inflammatory and anticancer activities (Aggarwal et al. 2013); whole turmeric may be better than curcumin alone

    Source: How Not to Die

Tips & Recommendations

  • Eat 1/4 teaspoon of turmeric daily

    Source: How Not to Die

  • Include a quarter teaspoon of turmeric daily with black pepper

    Source: How Not to Die

Recipes with Turmeric

Sources

  • How Not to Age
  • How Not to Die
  • Nutrition, Food and Diet in Ageing and Longevity