Resveratrol

Food Sources

Foods that contain Resveratrol.

• Grapes

  Resveratrol can be found in grape skin, and thus wine was celebrated as a longevity tonic.

  Source: How We Age

• Red Wine

  Resveratrol can be found in grape skin, and thus wine was celebrated as a longevity tonic (despite the fact that the amounts of wine that would be required to affect lifespan would be toxic many times over).; The red wine polyphenol resveratrol was the darling of the longevity field

  Source: How We Age

• Red Grapes

  Resveratrol, a compound present in the skin of red grapes and berries, seemed to have sirtuin-activating activity.; Resveratrol is a member of the class of small polyphenol molecules called stilbenes, which are primarily found in the skin of red grapes and other dark berries

  Source: How We Age

• Berries

  Resveratrol, a compound present in the skin of red grapes and berries.; Stilbenes, which are primarily found in the skin of red grapes and other dark berries

  Source: How We Age

• Raisins

  Resveratrol is often found in grapes, raisins, berries and peanuts

  Source: Nutrition, Food and Diet in Ageing and Longevity

• Peanuts

  Resveratrol is often found in grapes, raisins, berries and peanuts; Peanut sprouts (germinated peanuts) containing high amounts of resveratrol.

  Source: Nutrition, Food and Diet in Ageing and Longevity

• Dark Chocolate

  Resveratrol is abundant in red wine, blueberries and dark chocolate; Dark chocolate, blueberries, nuts, pomegranates, berries, and tea comprise of resveratrol in varying concentrations.

  Source: Nutrition, Food and Diet in Ageing and Longevity

• Blueberries

  Resveratrol is abundant in red wine, blueberries and dark chocolate; Blueberries comprise of resveratrol in varying concentrations.

  Source: Nutrition, Food and Diet in Ageing and Longevity

• Pomegranate

  Pomegranates comprise of resveratrol in varying concentrations.

  Source: Nutrition, Food and Diet in Ageing and Longevity

• Nuts

  Nuts comprise of resveratrol in varying concentrations.

  Source: Nutrition, Food and Diet in Ageing and Longevity

• Berries

  Rich in the phytonutrient resveratrol

  Source: The Young Forever Cookbook

Health Benefits

Health conditions that Resveratrol may influence, based on research.

Biological Mechanisms

How Resveratrol works at a cellular level.

• PromotesSirtuin Activation

  Most widely known STAC but purported sirtuin activity called into question; experimental artifact possible; largely disappointing in clinical trials

• PromotesSuppresses NF-kB signaling that drives cancer growth

  Resveratrol exhibits anti-inflammatory effects via suppression of NF-kB, JAK-STAT, and AP-1 signalling pathways

• PromotesActivates Nrf2

  Low concentrations (<50 microM) of resveratrol enhanced pool of endogenous reduced glutathione and Sirt1 expression via activation of the Nrf2 pathway

• PromotesHormesis

  Resveratrol (red grapes, peanuts) is a mitohormetin that directly binds to mitochondrial complex I

• PromotesSuppresses the inflammatory secretions of senescent cells (SASP)

  Resveratrol has the ability to remove ROS, inhibit cyclooxygenase (COX), and trigger anti-inflammatory pathways via SIRT1 activation. Multiple studies show that resveratrol can suppress SASP

• PromotesActivates or regenerates adult stem cells

  Resveratrol caused restoration of muscle mass associated with improvement of satellite cell proliferation; activates hematopoietic stem cells and cardiac stem cells

• PromotesProtects brain cells from damage

  Administration of resveratrol (20 mg/kg) to old rats enhanced neurogenesis in the hippocampus; in stressed models, resveratrol increased neonatal neurons and BDNF expression

• PromotesReduces neuroinflammation

  Resveratrol's effects on apoptosis, neuroinflammation and reduction of Aβ oligomers.

• PromotesReduces Amyloid Accumulation

  Resveratrol reduces brain amyloid-beta oligomers.

• PromotesInduces mitophagy

  Nutrients such as resveratrol, curcumin, astaxanthin and spermidine are increasingly being promoted as effective in enhancing mitophagy.

• PromotesPromotes fat burning and reduces fat creation

  Resveratrol has potential anti-obesity effects by promoting lipolysis and β-oxidation, reducing lipogenesis.

• PromotesCaloric Restriction Slows Aging

  Resveratrol initially seemed to extend lifespan in overweight mice, but other labs could not reproduce the findings; it failed to extend lifespan in rigorous testing

• InhibitsReduces Mortality Risk

  When resveratrol was subjected to rigorous testing it failed to extend lifespan in mice (Miller et al. 2011; Strong et al. 2013)

• PromotesAutophagy
• PromotesAMPK activation
• PromotesCalorie Restriction Mimicry

Recipes with Resveratrol

Recipes featuring foods that contain Resveratrol.

• Dr. Hyman's Healthy Aging Shake
• Roasted Pepper Medley with Pine Nut Salsa
• Dark Chocolate Seaweed Rounds
• Coconut and Chocolate Blueberry Clusters
• Quinoa, Cashew, and Dark Chocolate Squares
• Chewy Chocolate Coconut Cookies
• Dr. Fuhrman's Anti-Inflammatory Green Smoothie
• Three-Berry Groatnola with Date Syrup Drizzle
• Banana-Almond French Toast with Blueberries
• Blueberry Chia Pie
• Himalayan Tartary Buckwheat and Berry Pancakes
• Protein Powerhouse Smoothie
• Blueberry-Lavender Chia Jam
• Antioxidant Berry Smoothie
• Braised Pomegranate Lamb Shanks
• Smoky Roasted Pepper and Walnut Dip
• Zucchini Ribbons with Grilled Chicken and Preserved Lemon
• Beef Kofte with Hummus
• Mixed Berry and Almond Crisp

Sources

• How Not to Age
• How We Age
• Nutrition, Food and Diet in Ageing and Longevity
• The Young Forever Cookbook
• Young Forever
• Outlive